Local and Global Hopf bifurcation in a Delayed Hematopoiesis Model

We first consider the existence of local Hopf bifurcations, and then derive the explicit formulas which determine the stability, direction and other properties of bifurcating periodic solutions, using the normal form theory and center manifold reduction. Further, particular attention is focused on the existence of the global Hopf bifurcation. By using the global Hopf bifurcation theory due to Wu [1998], we show that the local Hopf bifurcation of (1) implies the global Hopf bifurcation after the second critical value of the delay τ . Finally, numerical simulation results are given to support the theoretical predictions.